| pubmed-article:1520786 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C0019994 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C0035648 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C0014507 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C0877445 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C2698872 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C0026565 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C1947933 | lld:lifeskim |
| pubmed-article:1520786 | lifeskim:mentions | umls-concept:C0205372 | lld:lifeskim |
| pubmed-article:1520786 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1520786 | pubmed:dateCreated | 1992-10-15 | lld:pubmed |
| pubmed-article:1520786 | pubmed:abstractText | Demographic information, risk factors, therapy, and outcome for all patients who had candidemia at Barnes Hospital, St. Louis, between 1 September 1988 and 1 September 1989 were retrospectively reviewed. One hundred six candidemic patients were identified, representing 0.5% of all medical and surgical discharges and 0.33% of total patient discharges. These percentages represent a 20-fold increase in the incidence of candidemia at our hospital in comparison with that during 1976-1979. Candida albicans was the most frequently isolated species (63%), followed by Candida tropicalis (17%), Candida glabrata (13%), Candida parapsilosis (6.5%), and Candida krusei (0.9%). Overall mortality was 57%, and 14 (23%) of 60 deaths occurred within 48 hours of the detection of candidemia. Mortality was associated with higher APACHE II scores (25 for nonsurvivors vs. 16 for survivors; P = .0001), the presence of a rapidly fatal underlying illness (P = .0009), and sustained positivity of blood cultures (P = .02). In cases of sustained candidemia, the isolation of non-albicans Candida species also correlated with increased mortality (8 of 8 vs. 10 of 21; P = .005). Thirty candidemic patients (28%) did not receive any antifungal therapy, and 19 (63%) of these untreated patients died. Eleven untreated patients (37%) survived without sequelae. There has been a marked increase in the incidence of candidemia in our institution that is associated with a high overall mortality. Candidemia lasting less than 24 hours was associated with a lower mortality than was that of longer duration. Severity of illness and duration of candidemia should be used as stratifying factors in prospective studies to determine optimum therapy. | lld:pubmed |
| pubmed-article:1520786 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1520786 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1520786 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1520786 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1520786 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1520786 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1520786 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1520786 | pubmed:issn | 1058-4838 | lld:pubmed |
| pubmed-article:1520786 | pubmed:author | pubmed-author:JonesMM | lld:pubmed |
| pubmed-article:1520786 | pubmed:author | pubmed-author:MedoffGG | lld:pubmed |
| pubmed-article:1520786 | pubmed:author | pubmed-author:DunkelJJ | lld:pubmed |
| pubmed-article:1520786 | pubmed:author | pubmed-author:FraserV JVJ | lld:pubmed |
| pubmed-article:1520786 | pubmed:author | pubmed-author:DunaganW CWC | lld:pubmed |
| pubmed-article:1520786 | pubmed:author | pubmed-author:StorferSS | lld:pubmed |
| pubmed-article:1520786 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1520786 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:1520786 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1520786 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1520786 | pubmed:pagination | 414-21 | lld:pubmed |
| pubmed-article:1520786 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:meshHeading | pubmed-meshheading:1520786-... | lld:pubmed |
| pubmed-article:1520786 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1520786 | pubmed:articleTitle | Candidemia in a tertiary care hospital: epidemiology, risk factors, and predictors of mortality. | lld:pubmed |
| pubmed-article:1520786 | pubmed:affiliation | Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. | lld:pubmed |
| pubmed-article:1520786 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1520786 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1520786 | pubmed:publicationType | Review | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1520786 | lld:pubmed |
