| pubmed-article:1519 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0017071 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0028778 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0004745 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:1519 | lifeskim:mentions | umls-concept:C0243144 | lld:lifeskim |
| pubmed-article:1519 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1519 | pubmed:dateCreated | 1976-3-30 | lld:pubmed |
| pubmed-article:1519 | pubmed:abstractText | The effects of two barbiturates on calcium uptake by sympathetic ganglia have been examined. Sodium pentobarbital (0.4-0.75 mM) and sodium thiopental (0.3 mM) block the preganglionic stimulation-induced uptake of 45Ca by rat superior cervical ganglia but not action potential conduction in the presynaptic axons. The ganglionic-blocking agent, tetraethylammonium, does not inhibit stimulation-induced Ca uptake and does not prevent the blocking effect of thiopental. This effect is therefore probably presynaptic. Postassium-rich media also stimulate Ca uptake by the ganglia, and this effect is markedly inhibited by pentobarbital. Since the K stimulation effect is also observed in deafferented ganglia but not in guanethidine-denervated ganglia, this effect is probably associated primarily with postsynaptic elements. In sum, the data suggest that the barbiturates inhibit Ca permeability changes in both pre- and postsynaptic neurons. | lld:pubmed |
| pubmed-article:1519 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1519 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1519 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1519 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1519 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1519 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1519 | pubmed:issn | 0022-3565 | lld:pubmed |
| pubmed-article:1519 | pubmed:author | pubmed-author:BlausteinM... | lld:pubmed |
| pubmed-article:1519 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1519 | pubmed:volume | 196 | lld:pubmed |
| pubmed-article:1519 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1519 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1519 | pubmed:pagination | 80-6 | lld:pubmed |
| pubmed-article:1519 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1519 | pubmed:meshHeading | pubmed-meshheading:1519-Gan... | lld:pubmed |
| pubmed-article:1519 | pubmed:meshHeading | pubmed-meshheading:1519-Gan... | lld:pubmed |
| pubmed-article:1519 | pubmed:meshHeading | pubmed-meshheading:1519-Dep... | lld:pubmed |
| pubmed-article:1519 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:1519 | pubmed:articleTitle | Barbiturates block calcium uptake by stimulated and potassium-depolarized rat sympathetic ganglia. | lld:pubmed |
| pubmed-article:1519 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1519 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:1519 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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