| pubmed-article:1517921 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1517921 | lifeskim:mentions | umls-concept:C0282667 | lld:lifeskim |
| pubmed-article:1517921 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:1517921 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:1517921 | lifeskim:mentions | umls-concept:C0006287 | lld:lifeskim |
| pubmed-article:1517921 | lifeskim:mentions | umls-concept:C0042839 | lld:lifeskim |
| pubmed-article:1517921 | lifeskim:mentions | umls-concept:C1515075 | lld:lifeskim |
| pubmed-article:1517921 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1517921 | pubmed:dateCreated | 1992-10-8 | lld:pubmed |
| pubmed-article:1517921 | pubmed:abstractText | We performed a randomized, double-blind, controlled trial to determine whether vitamin A supplementation in a group of very low birth weight infants would reduce the incidence of bronchopulmonary dysplasia. Forty-nine infants (birth weight 700 to 1100 gm) requiring mechanical ventilation and supplemental oxygen at 96 hours age were randomly assigned to receive either 2000 IU retinyl palmitate (n = 27) or saline placebo (n = 22) intramuscularly every other day for up to 14 doses. There were no differences between treatment groups in the incidences of bronchopulmonary dysplasia at 31 days of postnatal age (vitamin A group 48%, placebo group 55%; p = 0.776), supplemental oxygen requirement at 34 weeks of postconceptional age, or other complications of prematurity. The vitamin A group had higher mean plasma vitamin A concentrations than the placebo group, but mean plasma vitamin A concentrations were greater than 20 micrograms/dl (suggesting sufficiency) in both groups after the first study week. By study day 28, only one fourth of the infants in either group had plasma vitamin A concentrations less than 20 micrograms/dl. In contrast to an earlier report, we found no change in the incidence of BPD with vitamin A supplementation. Our findings may reflect a low baseline incidence of vitamin A deficiency in the study population and recent changes in the respiratory care of very low birth weight infants. The latter may have lessened the potential impact of vitamin A deficiency on lung disease. | lld:pubmed |
| pubmed-article:1517921 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1517921 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1517921 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1517921 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1517921 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1517921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1517921 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1517921 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1517921 | pubmed:issn | 0022-3476 | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:BosaCC | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:PearsonEE | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:YoungTT | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:BoseCC | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:RansonMM | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:SnidowTT | lld:pubmed |
| pubmed-article:1517921 | pubmed:author | pubmed-author:StilesAA | lld:pubmed |
| pubmed-article:1517921 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1517921 | pubmed:volume | 121 | lld:pubmed |
| pubmed-article:1517921 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1517921 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1517921 | pubmed:pagination | 420-7 | lld:pubmed |
| pubmed-article:1517921 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1517921 | pubmed:meshHeading | pubmed-meshheading:1517921-... | lld:pubmed |
| pubmed-article:1517921 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1517921 | pubmed:articleTitle | Trial of vitamin A supplementation in very low birth weight infants at risk for bronchopulmonary dysplasia. | lld:pubmed |
| pubmed-article:1517921 | pubmed:affiliation | Department of Pediatrics, University of North Carolina Hospital, Chapel Hill 27599-7596. | lld:pubmed |
| pubmed-article:1517921 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1517921 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:1517921 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:1517921 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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