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pubmed-article:15177524pubmed:abstractTextSerum creatinine and creatinine clearance are used as indicators of renal function and may indicate a propensity for development of end-stage renal disease. Identifying genes related to future decreases in renal function could be important in assessing risk and defining abnormal mechanisms amenable to preventive measures. Although creatinine clearance is a better measure of renal function than serum creatinine, proper and complete urine collections in large population studies are sometimes problematic. This can lead to a loss in power to detect linkage. Therefore, in this study we also investigated serum creatinine and estimated glomerular filtration rates (GFR), both of which are more reliably measured.lld:pubmed
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pubmed-article:15177524pubmed:articleTitleLinkage of serum creatinine and glomerular filtration rate to chromosome 2 in Utah pedigrees.lld:pubmed
pubmed-article:15177524pubmed:affiliationDepartment of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA. steve@ucvg.med.utah.edulld:pubmed
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