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pubmed-article:15136967pubmed:abstractTextHeart failure is a clinical syndrome that may result from different disease states or conditions that injure the myocardium. The activation of circulating neurohormones, particularly aldosterone, may play a pivotal role in left ventricular (LV) remodelling. The Randomized Aldactone Evaluation Study and Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival trial have emphasised the clinical importance of aldosterone. This review addresses some of the proposed mechanisms of LV remodelling in heart failure.lld:pubmed
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pubmed-article:15136967pubmed:authorpubmed-author:SamFloraFlld:pubmed
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pubmed-article:15136967pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:15136967pubmed:year2004lld:pubmed
pubmed-article:15136967pubmed:articleTitleAldosterone and cardiovascular remodelling: focus on myocardial failure.lld:pubmed
pubmed-article:15136967pubmed:affiliationBoston University Medical School, Boston University Medical Center, Boston, Massechussetts, USA.lld:pubmed
pubmed-article:15136967pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15136967pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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