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pubmed-article:15126878pubmed:abstractTextThe rather poor responses to conventional treatment for bladder cancer (BCa) require novel, specific therapy approaches. The down-regulation of BCa associated genes may represent a new option to inhibit specifically BCa cell growth and induce cell death. Survivin, an apoptosis inhibitor that is up-regulated in the majority of malignancies, including BCa, provides an attractive target for molecular therapies, such as treatment with specific antisense oligode-oxynucleotides (AS-ODNs).lld:pubmed
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pubmed-article:15126878pubmed:dateRevised2011-11-17lld:pubmed
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pubmed-article:15126878pubmed:articleTitleSystematic in vitro evaluation of survivin directed antisense oligodeoxynucleotides in bladder cancer cells.lld:pubmed
pubmed-article:15126878pubmed:affiliationDepartment of Urology and Institute of Pathology, Technical University Dresden, Dresden, Germany. susanne.fuessel@mailbox.tu-dresden.delld:pubmed
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