| pubmed-article:1512021 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0613707 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C1061163 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C2930158 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0036211 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0018270 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:1512021 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:1512021 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1512021 | pubmed:dateCreated | 1992-10-1 | lld:pubmed |
| pubmed-article:1512021 | pubmed:abstractText | Withania somnifera is a medicinal plant used in the treatment of a variety of ailments in the Ayurvedic system. Alcoholic extract of the root of the plant was injected(ip) at daily doses of 200 to 1000 mg/kg body wt for 15 days starting from 24 hr after intradermal inoculation of 5 x 10(5) cells of S-180 in BALB/c mice. Solid tumor growth was monitored for 100 days. Doses of 400 mg/kg and above produced complete regression of tumor after an initial growth, the percentage of complete response (CR) increasing with increasing drug dose. A 55% CR was obtained at 1000 mg/kg drug administration, but this dose also produced some mortality among the animals. A significant increase in the volume doubling time and growth delay was seen when the drug dose was increased from 500 to 750 mg/kg body wt, but further increase in drug dose to 1000 mg/kg did not produce any significant increase in these responses. Cumulative doses of 7.5 to 10 g at daily doses of 500 or 750 mg/kg seems to produce a good response in this tumor. | lld:pubmed |
| pubmed-article:1512021 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1512021 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1512021 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1512021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1512021 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1512021 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:1512021 | pubmed:issn | 0019-5189 | lld:pubmed |
| pubmed-article:1512021 | pubmed:author | pubmed-author:DeviP UPU | lld:pubmed |
| pubmed-article:1512021 | pubmed:author | pubmed-author:SharadaA CAC | lld:pubmed |
| pubmed-article:1512021 | pubmed:author | pubmed-author:SolomonF EFE | lld:pubmed |
| pubmed-article:1512021 | pubmed:author | pubmed-author:KamathM SMS | lld:pubmed |
| pubmed-article:1512021 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1512021 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:1512021 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1512021 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1512021 | pubmed:pagination | 169-72 | lld:pubmed |
| pubmed-article:1512021 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:meshHeading | pubmed-meshheading:1512021-... | lld:pubmed |
| pubmed-article:1512021 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1512021 | pubmed:articleTitle | In vivo growth inhibitory effect of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma 180. | lld:pubmed |
| pubmed-article:1512021 | pubmed:affiliation | Department of Radiobiology, Kasturba Medical College, Manipal, India. | lld:pubmed |
| pubmed-article:1512021 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1512021 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1512021 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1512021 | lld:pubmed |
