| pubmed-article:1511686 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C0007004 | lld:lifeskim |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C0016945 | lld:lifeskim |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C0023206 | lld:lifeskim |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C0439962 | lld:lifeskim |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C1881065 | lld:lifeskim |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C1882443 | lld:lifeskim |
| pubmed-article:1511686 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
| pubmed-article:1511686 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1511686 | pubmed:dateCreated | 1992-9-29 | lld:pubmed |
| pubmed-article:1511686 | pubmed:abstractText | Quantitative precipitation studies have shown that the Man/Glc-specific lectin concanavalin A (ConA) forms homogeneous (homopolymeric) cross-linked precipitates with individual asparagine-linked oligomannose and bisected hybrid-type glycopeptides in the presence of binary mixtures of the carbohydrates [Bhattacharyya, L., Khan, M. I. & Brewer, C. F. (1988) Biochemistry 27, 8762-8767]. The results indicate that the ConA-glycopeptide precipitates are highly organized cross-linked lattices that are unique for each carbohydrate. Using similar techniques, the present study shows that the Gal-specific lectins from Erythrina indica and Ricinus communis (agglutinin I) form homogeneous cross-linked complexes with individual carbohydrates in binary mixtures of triantennary and tetraantennary complex-type oligosaccharides with terminal Gal residues. Conversely, binary mixtures of Gal/GalNAc-specific lectins from E. indica, Erythrina cristagalli, Erythrina flabelliformis, R. communis, soybean (Glycine max), and Wistaria floribunda (tetramer) in the presence of a naturally occurring or synthetic branched-chain oligosaccharide with terminal GalNAc or Gal residues provide evidence for the formation of separate cross-linked lattices between each lectin and the carbohydrate. The present results therefore demonstrate the formation of homogeneous lectin-carbohydrate cross-linked lattices in (a) a mixture of branched-chain complex-type oligosaccharides in the presence of a specific Gal/GalNAc-binding lectin, and (b) a mixture of lectins with similar physicochemical and carbohydrate binding properties in the presence of an oligosaccharide. These findings show that lectin-carbohydrate cross-linking interactions provide a high degree of specificity which may be relevant to their biological functions as receptors. | lld:pubmed |
| pubmed-article:1511686 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1511686 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1511686 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1511686 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1511686 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1511686 | pubmed:issn | 0014-2956 | lld:pubmed |
| pubmed-article:1511686 | pubmed:author | pubmed-author:BrewerC FCF | lld:pubmed |
| pubmed-article:1511686 | pubmed:author | pubmed-author:Bhattacharyya... | lld:pubmed |
| pubmed-article:1511686 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1511686 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1511686 | pubmed:volume | 208 | lld:pubmed |
| pubmed-article:1511686 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1511686 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1511686 | pubmed:pagination | 179-85 | lld:pubmed |
| pubmed-article:1511686 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:meshHeading | pubmed-meshheading:1511686-... | lld:pubmed |
| pubmed-article:1511686 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1511686 | pubmed:articleTitle | Formation of homogeneous carbohydrate-lectin cross-linked precipitates from mixtures of D-galactose/N-acetyl-D-galactosamine-specific lectins and multiantennary galactosyl carbohydrates. | lld:pubmed |
| pubmed-article:1511686 | pubmed:affiliation | Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461. | lld:pubmed |
| pubmed-article:1511686 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1511686 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1511686 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1511686 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1511686 | lld:pubmed |
