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pubmed-article:15112225pubmed:dateCreated2004-4-27lld:pubmed
pubmed-article:15112225pubmed:abstractTextThe reconstruction of bacterial evolutionary relationships has proven to be a daunting task because variable mutation rates and horizontal gene transfer (HGT) among species can cause grave incongruities between phylogenetic trees based on single genes. Recently, a highly robust phylogenetic tree was constructed for 13 gamma-proteobacteria using the combined alignments of 205 conserved orthologous proteins.1 Only two proteins had incongruent tree topologies, which were attributed to HGT between Pseudomonas species and Vibrio cholerae or enterics. While the evolutionary relationships among these species appears to be resolved, further analysis suggests that HGT events with other bacterial partners likely occurred; this alters the implicit assumption of gamma-proteobacteria monophyly. Thus, any thorough reconstruction of bacterial evolution must not only choose a suitable set of molecular markers but also strive to reduce potential bias in the selection of species.lld:pubmed
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pubmed-article:15112225pubmed:monthMaylld:pubmed
pubmed-article:15112225pubmed:issn0265-9247lld:pubmed
pubmed-article:15112225pubmed:authorpubmed-author:BrownJames...lld:pubmed
pubmed-article:15112225pubmed:authorpubmed-author:VolkerCraigClld:pubmed
pubmed-article:15112225pubmed:copyrightInfoCopyright 2004 Wiley Periodicals, Inc.lld:pubmed
pubmed-article:15112225pubmed:issnTypePrintlld:pubmed
pubmed-article:15112225pubmed:volume26lld:pubmed
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pubmed-article:15112225pubmed:pagination463-8lld:pubmed
pubmed-article:15112225pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:15112225pubmed:year2004lld:pubmed
pubmed-article:15112225pubmed:articleTitlePhylogeny of gamma-proteobacteria: resolution of one branch of the universal tree?lld:pubmed
pubmed-article:15112225pubmed:affiliationBioinformatics Division, Genetics Research, GlaxoSmithKline, Collegeville, Pennsylvania 19426-0989, USA. James.R.Brown@gsk.comlld:pubmed
pubmed-article:15112225pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15112225pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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