| pubmed-article:151097 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0036126 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0015861 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0243144 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:151097 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:151097 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:151097 | pubmed:dateCreated | 1978-11-29 | lld:pubmed |
| pubmed-article:151097 | pubmed:abstractText | Two high-affinity iron uptake systems are known in Salmonella typhimurium, one utilizing iron-enterochelin and the other utilizing ferrichrome. It has been shown previously that expression of several elements of the iron-enterochelin uptake system are regulated by the iron content of the medium, with growth in high-iron medium resulting in repression of enzymes of enterochelin synthesis and degradation and of the ability of whole cells to take up iron-enterochelin. In this study we describe a mutant strain in which growth in high-iron medium was associated with constitutive expression of: (i) iron-enterochelin uptake by whole cells; (ii) ferrichrome uptake by whole cells; (iii) synthesis of enterochelin; (iv) intracellular degradation of iron-enterochelin; and (v) synthesis of three major outer membrane proteins (OM1, OM2, and OM3). In contrast, in the wild-type strain these properties were expressed only after growth in iron-deficient medium. It is proposed that the mutation affects a gene responsible for regulating expression of the structural genes for the components of the high-affinity iron uptake systems. The term fur, for iron (Fe) uptake regulation, is suggested for this new class of mutant. | lld:pubmed |
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| pubmed-article:151097 | pubmed:language | eng | lld:pubmed |
| pubmed-article:151097 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:151097 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:151097 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:151097 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:151097 | pubmed:issn | 0021-9193 | lld:pubmed |
| pubmed-article:151097 | pubmed:author | pubmed-author:ErnstJ FJF | lld:pubmed |
| pubmed-article:151097 | pubmed:author | pubmed-author:BennettR LRL | lld:pubmed |
| pubmed-article:151097 | pubmed:author | pubmed-author:RothfieldL... | lld:pubmed |
| pubmed-article:151097 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:151097 | pubmed:volume | 135 | lld:pubmed |
| pubmed-article:151097 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:151097 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:151097 | pubmed:pagination | 928-34 | lld:pubmed |
| pubmed-article:151097 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:151097 | pubmed:year | 1978 | lld:pubmed |
| pubmed-article:151097 | pubmed:articleTitle | Constitutive expression of the iron-enterochelin and ferrichrome uptake systems in a mutant strain of Salmonella typhimurium. | lld:pubmed |
| pubmed-article:151097 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:151097 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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