| pubmed-article:15081635 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0015934 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0032043 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0032914 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0232989 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C1705822 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0376335 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0348011 | lld:lifeskim |
| pubmed-article:15081635 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:15081635 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:15081635 | pubmed:dateCreated | 2004-4-14 | lld:pubmed |
| pubmed-article:15081635 | pubmed:abstractText | Magnetic resonance imaging provides a non-invasive method for investigating functional changes in the human placenta in vivo. In this study, we combine a magnetic resonance imaging technique called magnetization transfer with established stereological methods in order to analyse and compare placentae from normal (16-36 weeks of gestation) and complicated (pre-eclampsia, intrauterine growth restriction) pregnancies. Magnetization transfer provided an in vivo measure of the ratio of bound protons:total protons and stereological analysis of histological sections was used to estimate a residual:total volume ratio (the ratio of non-vascular volume to total placental volume). Statistical comparisons were drawn using tests for related samples (longitudinal data) or one-way analysis of variance (cross-sectional data). We found no significant differences in magnetization transfer between gestational age groups or between uncomplicated pregnancies and pregnancies complicated by pre-eclampsia or intrauterine growth restriction. In comparable groups of different subjects, stereological analyses also failed to demonstrate significant differences in residual:total volume ratios. We conclude that [a] the ratio of non-vascular volume:total placental volume does not alter between 16 and 36 weeks of normal gestation, and [b] this integrated response is also conserved in pre-eclampsia and intrauterine growth restriction. | lld:pubmed |
| pubmed-article:15081635 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15081635 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15081635 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15081635 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15081635 | pubmed:month | May | lld:pubmed |
| pubmed-article:15081635 | pubmed:issn | 0143-4004 | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:MooreR JRJ | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:JohnsonI RIR | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:BakerP NPN | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:MayhewT MTM | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:TylerD JDJ | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:GowlandP APA | lld:pubmed |
| pubmed-article:15081635 | pubmed:author | pubmed-author:DAYF LFL | lld:pubmed |
| pubmed-article:15081635 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15081635 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:15081635 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15081635 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15081635 | pubmed:pagination | 408-12 | lld:pubmed |
| pubmed-article:15081635 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:meshHeading | pubmed-meshheading:15081635... | lld:pubmed |
| pubmed-article:15081635 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15081635 | pubmed:articleTitle | Functional magnetic resonance imaging (magnetization transfer) and stereological analysis of human placentae in normal pregnancy and in pre-eclampsia and intrauterine growth restriction. | lld:pubmed |
| pubmed-article:15081635 | pubmed:affiliation | Department of Obstetrics and Gynecology, School of Human Development, City Hospital, University of Nottingham, Hucknall Road, Nottingham NG5 1PB, UK. stephenong888@hotmail.com | lld:pubmed |
| pubmed-article:15081635 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15081635 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:15081635 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15081635 | lld:pubmed |
