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pubmed-article:15066007pubmed:abstractTextThe enteric nervous system in combination with inputs from parasympathetic and sympathetic nerves regulate the contractile, secretory and vasomotor activity of the gastrointestinal track via neural reflexes. Sensory elements which may be present in specialized neurones, enteroendocrine cells or mast cells detect changes in force, chemical composition or even foreign antigens. Sensory elements signal the enteric nervous system to correct these changes by altering contractile activity, secretion and blood flow. Advances have been made in understanding the sensory mechanisms that are involved in 5-hydroxytryptamine (5-HT) release from enterochromaffin cells (EC) or a model for EC cells. These advances relate to roles for ATP and its metabolites ADP and adenosine in mechanotransduction and a role for a sodium glucose cotransporter, a SGLT-like protein, in chemotransduction.lld:pubmed
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pubmed-article:15066007pubmed:authorpubmed-author:CookeH JHJlld:pubmed
pubmed-article:15066007pubmed:authorpubmed-author:RaybouldH EHElld:pubmed
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pubmed-article:15066007pubmed:volume16 Suppl 1lld:pubmed
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pubmed-article:15066007pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:15066007pubmed:year2004lld:pubmed
pubmed-article:15066007pubmed:articleTitleSensory mechanisms: transmitters, modulators and reflexes.lld:pubmed
pubmed-article:15066007pubmed:affiliationDepartment of Anatomy, Physiology and Cell Biology, University of California Davis School of Veterinary Medicine, Davis, CA, USA. heraybould@ucdavis.edulld:pubmed
pubmed-article:15066007pubmed:publicationTypeJournal Articlelld:pubmed
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