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pubmed-article:15057971pubmed:abstractTextSpectral karyotyping and multiple fluorophore fluorescence in situ hybridisation (M-FISH) facilitate identification of inter-chromosomal rearrangements, but are of low cytogenetic resolution in mapping translocation breakpoints. Reverse chromosome painting yields increased cytogenetic information but isolation of aberrant chromosomes is technically difficult. We have developed the technique of paint-assisted microdissection FISH (PAM-FISH), which enables microdissection of aberrant chromosomes to be carried out easily and rapidly using relatively simple apparatus.lld:pubmed
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pubmed-article:15057971pubmed:authorpubmed-author:RobertsIanIlld:pubmed
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pubmed-article:15057971pubmed:authorpubmed-author:NachevaElisab...lld:pubmed
pubmed-article:15057971pubmed:copyrightInfoCopyright 2004 Wiley-Liss, Inc.lld:pubmed
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pubmed-article:15057971pubmed:volume58lld:pubmed
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pubmed-article:15057971pubmed:pagination177-84lld:pubmed
pubmed-article:15057971pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:15057971pubmed:year2004lld:pubmed
pubmed-article:15057971pubmed:articleTitlePaint-assisted microdissection-FISH: Rapid and simple mapping of translocation breakpoints in the embryonal rhabdomyosarcoma cell line RD.lld:pubmed
pubmed-article:15057971pubmed:affiliationMedical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, Cambridge, United Kingdom. ir210@cam.ac.uklld:pubmed
pubmed-article:15057971pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15057971pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:15057971pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed