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pubmed-article:15047232pubmed:abstractTextOvarian carcinoma cells form multicellular aggregates, or spheroids, in the peritoneal cavity of patients with advanced disease. The current paradigm that ascites spheroids are non-adhesive leaves their contribution to ovarian carcinoma dissemination undefined. Here, spheroids obtained from ovarian carcinoma patients' ascites were characterized for their ability to adhere to molecules encountered in the peritoneal cavity, with the goal of establishing their potential to contribute to ovarian cancer spread.lld:pubmed
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pubmed-article:15047232pubmed:articleTitleOvarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers.lld:pubmed
pubmed-article:15047232pubmed:affiliationDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA.lld:pubmed
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