| pubmed-article:15026039 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C0087162 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C0030011 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C1514468 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C0596495 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:15026039 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:15026039 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:15026039 | pubmed:dateCreated | 2004-3-17 | lld:pubmed |
| pubmed-article:15026039 | pubmed:abstractText | PdxA (E.C. 1.1.1.262) catalyzes a key step in the biosynthesis of vitamin B(6): the nicotinamide-dependent oxidation of 4-hydroxy-l-threonine-4-phosphate (HTP) to a product tentatively identified as 3-amino-1-hydroxyacetone 1-phosphate (AHAP). To date, the evidence for the formation of AHAP, while self-consistent, has been largely circumstantial, and does not exclude the possibility that the actual product of the enzyme-catalyzed oxidation of HTP might be 2-amino-3-oxo-4-hydroxybutyric acid 4-phosphate which could undergo rapid, non-enzyme-catalyzed decarboxylation once released from the protein. Use of negative ion electrospray ionization mass spectrometry (ESI-MS) and tandem mass spectrometric analysis (MS-MS) confirms that AHAP is the product of the PdxA-catalyzed reaction. | lld:pubmed |
| pubmed-article:15026039 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15026039 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15026039 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15026039 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15026039 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:15026039 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:15026039 | pubmed:author | pubmed-author:CaneDavid EDE | lld:pubmed |
| pubmed-article:15026039 | pubmed:author | pubmed-author:BanksJerelJ | lld:pubmed |
| pubmed-article:15026039 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15026039 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:15026039 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:15026039 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15026039 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15026039 | pubmed:pagination | 1633-6 | lld:pubmed |
| pubmed-article:15026039 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:meshHeading | pubmed-meshheading:15026039... | lld:pubmed |
| pubmed-article:15026039 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15026039 | pubmed:articleTitle | Biosynthesis of vitamin B6: direct identification of the product of the PdxA-catalyzed oxidation of 4-hydroxy-l-threonine-4-phosphate using electrospray ionization mass spectrometry. | lld:pubmed |
| pubmed-article:15026039 | pubmed:affiliation | Department of Chemistry, Box H, Brown University, Providence, Rhode Island, 02912-9108, USA. | lld:pubmed |
| pubmed-article:15026039 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15026039 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15026039 | lld:chembl |
| entrez-gene:944919 | entrezgene:pubmed | pubmed-article:15026039 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15026039 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15026039 | lld:pubmed |
