| pubmed-article:15006396 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15006396 | lifeskim:mentions | umls-concept:C1412727 | lld:lifeskim |
| pubmed-article:15006396 | lifeskim:mentions | umls-concept:C0332256 | lld:lifeskim |
| pubmed-article:15006396 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:15006396 | lifeskim:mentions | umls-concept:C0205250 | lld:lifeskim |
| pubmed-article:15006396 | lifeskim:mentions | umls-concept:C0163816 | lld:lifeskim |
| pubmed-article:15006396 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:15006396 | pubmed:dateCreated | 2004-3-9 | lld:pubmed |
| pubmed-article:15006396 | pubmed:abstractText | Recently, we reported a novel substrate-based octapeptide BACE1 inhibitor KMI-008 containing hydroxymethylcarbonyl (HMC) isostere as a transition-state mimic. Using KMI-008 as a lead compound, a small-sized and highly potent BACE1 inhibitor KMI-370 (IC(50)=3.4 nM) was designed and synthesized. | lld:pubmed |
| pubmed-article:15006396 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15006396 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15006396 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15006396 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:15006396 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:LiuPingP | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:IshiuraShoich... | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:KimuraTooruT | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:KisoYoshiakiY | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:SaidoTakaomi... | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:HamadaTakashi... | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:KasaiSokoS | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:HayashiYoshio... | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:HattoriChinat... | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:AsaiMasashiM | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:KitazumeShino... | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:HidakaKoushiK | lld:pubmed |
| pubmed-article:15006396 | pubmed:author | pubmed-author:ShutoDaisukeD | lld:pubmed |
| pubmed-article:15006396 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15006396 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:15006396 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:15006396 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15006396 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15006396 | pubmed:pagination | 1527-31 | lld:pubmed |
| pubmed-article:15006396 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:meshHeading | pubmed-meshheading:15006396... | lld:pubmed |
| pubmed-article:15006396 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15006396 | pubmed:articleTitle | KMI-358 and KMI-370, highly potent and small-sized BACE1 inhibitors containing phenylnorstatine. | lld:pubmed |
| pubmed-article:15006396 | pubmed:affiliation | Department of Medicinal Chemistry, Center for Frontier Research in Medicinal Science, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8412, Japan. | lld:pubmed |
| pubmed-article:15006396 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15006396 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15006396 | lld:chembl |
