| pubmed-article:15003872 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C1537056 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C0024398 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C1622204 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C0332157 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C0042196 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:15003872 | lifeskim:mentions | umls-concept:C0443252 | lld:lifeskim |
| pubmed-article:15003872 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:15003872 | pubmed:dateCreated | 2004-3-8 | lld:pubmed |
| pubmed-article:15003872 | pubmed:abstractText | The potential of vaccine-elicited anti-HIV envelope antibodies to control HIV-infection was evaluated by immunizing macaques with the HIV envelope protein and transiently depleting them of their CD8+ cells before intravenous challenge with the pathogenic CCR5-tropic SIV/HIV chimeric virus, SHIV(SF162P4). Although sterilizing immunity was not achieved, all vaccinated animals effectively controlled infection and remained free of disease for the duration of observation (over 3 years). In contrast, during the same period, the control animals progressed to disease. Both the vaccinees and the controls developed robust cell-mediated antiviral and neutralizing antibody responses following infection. A comparative analysis of these responses suggests that the more effective long-term control of infection by the vaccinated animals is due to the more rapid development of anti-HIV envelope antibodies. These studies suggest that priming by vaccination of B cell anti-HIV envelope responses maybe crucial for the long-term control of HIV infection. | lld:pubmed |
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| pubmed-article:15003872 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15003872 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15003872 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15003872 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15003872 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15003872 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:15003872 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:BlanchardJame... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:GettieAgegneh... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:SafritJeffrey... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:BarnettSusan... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:StamatatosLeo... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:BucknerClaris... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:VojtechLuciaL | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:SrivastavaInd... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:GinesLeoned... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:SaundersChery... | lld:pubmed |
| pubmed-article:15003872 | pubmed:author | pubmed-author:BohmRudolphR | lld:pubmed |
| pubmed-article:15003872 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15003872 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:15003872 | pubmed:volume | 320 | lld:pubmed |
| pubmed-article:15003872 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15003872 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15003872 | pubmed:pagination | 167-80 | lld:pubmed |
| pubmed-article:15003872 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:15003872 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15003872 | pubmed:articleTitle | Priming B cell-mediated anti-HIV envelope responses by vaccination allows for the long-term control of infection in macaques exposed to a R5-tropic SHIV. | lld:pubmed |
| pubmed-article:15003872 | pubmed:affiliation | Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA. | lld:pubmed |
| pubmed-article:15003872 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15003872 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:15003872 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15003872 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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