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pubmed-article:1500365pubmed:issue6lld:pubmed
pubmed-article:1500365pubmed:dateCreated1992-9-14lld:pubmed
pubmed-article:1500365pubmed:abstractTextA series of 1 beta-methylcarbapenem compounds, which have a 5'-substituted-N-methylpyrrolidin-3'-ylthio group as a C-2 side chain, have been prepared and their biological properties were investigated. Substitution with a methyl group on the nitrogen atom in the C-2 side chain effectively enhanced stability to renal dehydropeptidase-I as well as introduction of methylene spacer between the aminocarbonyl group and the pyrrolidine ring of the 5'-aminocarbonylpyrrolidin-3'-ylthio group.lld:pubmed
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pubmed-article:1500365pubmed:statusMEDLINElld:pubmed
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pubmed-article:1500365pubmed:issn0021-8820lld:pubmed
pubmed-article:1500365pubmed:authorpubmed-author:MatsumuraHHlld:pubmed
pubmed-article:1500365pubmed:authorpubmed-author:InoueTTlld:pubmed
pubmed-article:1500365pubmed:authorpubmed-author:SunagawaMMlld:pubmed
pubmed-article:1500365pubmed:authorpubmed-author:FukasawaMMlld:pubmed
pubmed-article:1500365pubmed:authorpubmed-author:YamagaHHlld:pubmed
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pubmed-article:1500365pubmed:volume45lld:pubmed
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pubmed-article:1500365pubmed:pagination971-6lld:pubmed
pubmed-article:1500365pubmed:dateRevised2000-12-18lld:pubmed
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pubmed-article:1500365pubmed:year1992lld:pubmed
pubmed-article:1500365pubmed:articleTitleSynthesis and biological properties of 1 beta-methylcarbapenems with N-methylpyrrolidinylthio group at C-2 position.lld:pubmed
pubmed-article:1500365pubmed:affiliationResearch Laboratories, Sumitomo Pharmaceuticals Co., Ltd., Osaka, Japan.lld:pubmed
pubmed-article:1500365pubmed:publicationTypeJournal Articlelld:pubmed