Linked Life Data

14998303

Source:http://linkedlifedata.com/resource/pubmed/id/14998303

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pubmed-article:14998303pubmed:abstractTextA possible mutagenic effect of 2.45 GHz radiofrequency exposure was examined using lacZ-transgenic Muta mice. Pregnant animals were exposed intermittently at a whole-body averaged specific absorption rate of 0.71 W/kg (10 seconds on, 50 seconds off which is 4.3 W/kg during the 10 seconds exposure). Offspring that were exposed in utero for 16 hours a day, from the embryonic age of 0 to 15 days, were examined at 10 weeks of age. To minimize thermal effects, the exposure was given in repeated bursts of 10 seconds of exposure followed by 50 seconds of no exposure. Mutation frequencies at the lacZ gene in spleen, liver, brain, and testis were similar to those observed in non-exposed mice. Quality of mutation assessed by sequencing the nucleotides of mutant DNAs revealed no appreciable difference between exposed and non-exposed samples. The data suggest that the level of radiofrequency exposure studied is not mutagenic when administered in utero in short repeated bursts.lld:pubmed
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pubmed-article:14998303pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:14998303pubmed:year2004lld:pubmed
pubmed-article:14998303pubmed:articleTitleAbsence of mutagenic effects of 2.45 GHz radiofrequency exposure in spleen, liver, brain, and testis of lacZ-transgenic mouse exposed in utero.lld:pubmed
pubmed-article:14998303pubmed:affiliationDepartment of Cell Biology, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan. tono@mail.tains.tohoku.ac.jplld:pubmed
pubmed-article:14998303pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:14998303pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed