| pubmed-article:14984932 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14984932 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:14984932 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
| pubmed-article:14984932 | lifeskim:mentions | umls-concept:C0033413 | lld:lifeskim |
| pubmed-article:14984932 | lifeskim:mentions | umls-concept:C1847895 | lld:lifeskim |
| pubmed-article:14984932 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:14984932 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:14984932 | pubmed:dateCreated | 2004-2-26 | lld:pubmed |
| pubmed-article:14984932 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14984932 | pubmed:abstractText | The gene for LPTS/PinX1 encodes a potent telomerase inhibitor and suppresses tumor cell growth. In order to investigate the transcriptional regulation of this gene, we isolated its 5'-flanking region from the human genomic BAC clone and identified a major transcriptional initiation site. The sequence of the 5'-flanking region is GC-rich, lacks canonical TATA box, but contains potential binding sites for a variety of transcription factors. The deletion analysis indicated that the proximal 100 bp (from nt -66 to +34) is essential for minimal promoter activity and the regions of promoter from nt -1272 to -573 and nt -330 to -66 are required for maximal expression of the LPTS/PinX1 gene. Four DNase I hypersensitive sites (DHS1-4) mapping to the regions of transcription initiation and promoter in LPTS/Pinx1 gene were also revealed. | lld:pubmed |
| pubmed-article:14984932 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14984932 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14984932 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14984932 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14984932 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14984932 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14984932 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14984932 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14984932 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:14984932 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:14984932 | pubmed:author | pubmed-author:ZhaoMujunM | lld:pubmed |
| pubmed-article:14984932 | pubmed:author | pubmed-author:LiTsaipingT | lld:pubmed |
| pubmed-article:14984932 | pubmed:author | pubmed-author:LiaoChengC | lld:pubmed |
| pubmed-article:14984932 | pubmed:author | pubmed-author:WangSuiquanS | lld:pubmed |
| pubmed-article:14984932 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14984932 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:14984932 | pubmed:volume | 1676 | lld:pubmed |
| pubmed-article:14984932 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14984932 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14984932 | pubmed:pagination | 261-5 | lld:pubmed |
| pubmed-article:14984932 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:meshHeading | pubmed-meshheading:14984932... | lld:pubmed |
| pubmed-article:14984932 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:14984932 | pubmed:articleTitle | Cloning and characterization of the promoter region of human LPTS/PinX1 gene. | lld:pubmed |
| pubmed-article:14984932 | pubmed:affiliation | State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China. | lld:pubmed |
| pubmed-article:14984932 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14984932 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:54984 | entrezgene:pubmed | pubmed-article:14984932 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:14984932 | lld:entrezgene |
