| pubmed-article:1498374 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1498374 | lifeskim:mentions | umls-concept:C0002171 | lld:lifeskim |
| pubmed-article:1498374 | lifeskim:mentions | umls-concept:C0034819 | lld:lifeskim |
| pubmed-article:1498374 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1498374 | pubmed:dateCreated | 1992-9-17 | lld:pubmed |
| pubmed-article:1498374 | pubmed:abstractText | Interleukin-2 (IL-2) is a lymphokine produced by activated T cells and its receptor (IL-2R) is expressed on T cells; one of the IL-2R components can be measured as a soluble serum protein (sIL-2R). Levels of sIL-2R were measured as a sign of T cell activation in serum of 12 patients suffering from alopecia areata (totalis or universalis) and in a group of healthy control subjects. An enzyme-linked immunosorbent assay was used to determine the levels of sIL-2R in blood samples drawn during both the active and resting phase of the disease. In patients with alopecia areata in active phase the sIL-2R concentrations were significantly higher than in stable phase and in controls. The biologic role of sIL-2R is still unknown, but one could speculate that T lymphocyte activation with subsequent secretion of IL-2 and IL-2R expression may contribute to the immune inflammatory mechanism of alopecia areata. | lld:pubmed |
| pubmed-article:1498374 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1498374 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1498374 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1498374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1498374 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1498374 | pubmed:issn | 1018-8665 | lld:pubmed |
| pubmed-article:1498374 | pubmed:author | pubmed-author:CainelliTT | lld:pubmed |
| pubmed-article:1498374 | pubmed:author | pubmed-author:MartinsHH | lld:pubmed |
| pubmed-article:1498374 | pubmed:author | pubmed-author:ValsecchiRR | lld:pubmed |
| pubmed-article:1498374 | pubmed:author | pubmed-author:ImbertiGG | lld:pubmed |
| pubmed-article:1498374 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1498374 | pubmed:volume | 184 | lld:pubmed |
| pubmed-article:1498374 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1498374 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1498374 | pubmed:pagination | 126-8 | lld:pubmed |
| pubmed-article:1498374 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:meshHeading | pubmed-meshheading:1498374-... | lld:pubmed |
| pubmed-article:1498374 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1498374 | pubmed:articleTitle | Alopecia areata and interleukin-2 receptor. | lld:pubmed |
| pubmed-article:1498374 | pubmed:affiliation | Department of Dermatology, Ospedali Riuniti, Bergamo, Italy. | lld:pubmed |
| pubmed-article:1498374 | pubmed:publicationType | Journal Article | lld:pubmed |
