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pubmed-article:14982117pubmed:abstractTextExtracellular phospholipase production by environmental and clinical isolates of Aspergillus fumigatus collected from several centres world-wide were compared. All isolates produced extracellular phospholipases which included phospholipase C and a phospholipid acyl hydrolase (phospholipase A and/or phospholipase B) activity. Clinical isolates of A. fumigatus produced the largest zone sizes in a diffusion assay and clinical isolates produced more extracellular phospholipase C than environmental isolates. However, environmental isolates of A. fumigatus showed increased acyl hydrolase activity compared to clinical isolates of A. fumigatus. This study suggests that extracellular phospholipase C activity, but not extracellular acyl hydrolase activity may be important in the pathogenicity of A. fumigatus.lld:pubmed
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pubmed-article:14982117pubmed:authorpubmed-author:RobsonGeoffre...lld:pubmed
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pubmed-article:14982117pubmed:volume42lld:pubmed
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pubmed-article:14982117pubmed:pagination81-6lld:pubmed
pubmed-article:14982117pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:14982117pubmed:year2004lld:pubmed
pubmed-article:14982117pubmed:articleTitleComparison of extracellular phospholipase activities in clinical and environmental Aspergillus fumigatus isolates.lld:pubmed
pubmed-article:14982117pubmed:affiliationUniversity of Manchester, Department of Medicine, Hope Hospital, Salford, UK.lld:pubmed
pubmed-article:14982117pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:14982117pubmed:publicationTypeComparative Studylld:pubmed
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