pubmed-article:14981140 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:14981140 | lifeskim:mentions | umls-concept:C0700038 | lld:lifeskim |
pubmed-article:14981140 | lifeskim:mentions | umls-concept:C0084692 | lld:lifeskim |
pubmed-article:14981140 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:14981140 | pubmed:dateCreated | 2004-2-24 | lld:pubmed |
pubmed-article:14981140 | pubmed:abstractText | Surfactant protein D (SP-D) plays a role in innate immunity against various pathogens and in vivo studies have demonstrated that SP-D also has anti-inflammatory properties. SP-D was originally demonstrated in alveolar type II cells, but recent studies have shown extrapulmonary expression of SP-D indicating a systemic role for the protein. This study describes the presence of SP-D in the female genital tract, the placenta and in amniotic fluid using immunohistochemistry and enzyme-linked immunosorbent assay. SP-D was observed in cells lining surface epithelium and secretory glands in the vagina, cervix, uterus, fallopian tubes and ovaries. In the placenta, SP-D was seen in all villous and extravillous trophoblast subpopulations. Endometrial presence of SP-D in non-pregnant women varied according to stage of the menstrual cycle and was up-regulated towards the secretory phase. It is suggested that endometrial SP-D may prevent intrauterine infection at the time of implantation and during pregnancy. | lld:pubmed |
pubmed-article:14981140 | pubmed:language | eng | lld:pubmed |
pubmed-article:14981140 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:14981140 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:14981140 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:14981140 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:14981140 | pubmed:month | Mar | lld:pubmed |
pubmed-article:14981140 | pubmed:issn | 1360-9947 | lld:pubmed |
pubmed-article:14981140 | pubmed:author | pubmed-author:NielsenOO | lld:pubmed |
pubmed-article:14981140 | pubmed:author | pubmed-author:HolmskovUU | lld:pubmed |
pubmed-article:14981140 | pubmed:author | pubmed-author:FloridonCC | lld:pubmed |
pubmed-article:14981140 | pubmed:author | pubmed-author:Leth-LarsenRR | lld:pubmed |
pubmed-article:14981140 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:14981140 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:14981140 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:14981140 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:14981140 | pubmed:pagination | 149-54 | lld:pubmed |
pubmed-article:14981140 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:14981140 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:14981140 | pubmed:articleTitle | Surfactant protein D in the female genital tract. | lld:pubmed |
pubmed-article:14981140 | pubmed:affiliation | Immunology and Microbiology, Institute of Medical Biology, University of Southern Denmark, Winsloewparken 21, DK-5000 Odense C, Denmark. | lld:pubmed |
pubmed-article:14981140 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:14981140 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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