| pubmed-article:14980678 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14980678 | lifeskim:mentions | umls-concept:C0002482 | lld:lifeskim |
| pubmed-article:14980678 | lifeskim:mentions | umls-concept:C1827106 | lld:lifeskim |
| pubmed-article:14980678 | lifeskim:mentions | umls-concept:C2917254 | lld:lifeskim |
| pubmed-article:14980678 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:14980678 | pubmed:dateCreated | 2004-2-24 | lld:pubmed |
| pubmed-article:14980678 | pubmed:abstractText | Amides derived from fluorinated pyrrolidines and 4-substituted cyclohexylglycine analogues have been prepared and evaluated as inhibitors of dipeptidyl dipeptidase IV (DP-IV). Analogues which incorporated (S)-3-fluoropyrrolidine showed good selectivity for DP-IV over quiescent cell proline dipeptidase (QPP). Compound 48 had good pharmacokinetic properties and was orally active in an oral glucose tolerance test in lean mice. | lld:pubmed |
| pubmed-article:14980678 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14980678 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14980678 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14980678 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:14980678 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:ChenPingP | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:LyonsKathryn... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:WeberAnn EAE | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:ThornberryNan... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:CaldwellCharl... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:LeitingBarbar... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:WuJoseph KJK | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:MarsilioFrank... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:PatelReshma... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:HeJiafangJ | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:ParmeeEmma... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:HeHuaibingH | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:PetrovAleksan... | lld:pubmed |
| pubmed-article:14980678 | pubmed:author | pubmed-author:EiermannGeorg... | lld:pubmed |
| pubmed-article:14980678 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14980678 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:14980678 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:14980678 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14980678 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14980678 | pubmed:pagination | 1265-8 | lld:pubmed |
| pubmed-article:14980678 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
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| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
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| pubmed-article:14980678 | pubmed:meshHeading | pubmed-meshheading:14980678... | lld:pubmed |
| pubmed-article:14980678 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:14980678 | pubmed:articleTitle | Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors. | lld:pubmed |
| pubmed-article:14980678 | pubmed:affiliation | Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA. chuck_caldwell@merck.com | lld:pubmed |
| pubmed-article:14980678 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14980678 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:14980678 | lld:chembl |
