| pubmed-article:14976315 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14976315 | lifeskim:mentions | umls-concept:C0079337 | lld:lifeskim |
| pubmed-article:14976315 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:14976315 | lifeskim:mentions | umls-concept:C1420812 | lld:lifeskim |
| pubmed-article:14976315 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:14976315 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:14976315 | pubmed:issue | 5661 | lld:pubmed |
| pubmed-article:14976315 | pubmed:dateCreated | 2004-2-20 | lld:pubmed |
| pubmed-article:14976315 | pubmed:abstractText | Feline immunodeficiency virus (FIV) induces a disease similar to acquired immunodeficiency syndrome (AIDS) in cats, yet in contrast to human immunodeficiency virus (HIV), CD4 is not the viral receptor. We identified a primary receptor for FIV as CD134 (OX40), a T cell activation antigen and costimulatory molecule. CD134 expression promotes viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Infection is CXCR4-dependent, analogous to infection with X4 strains of HIV. Thus, despite the evolutionary divergence of the feline and human lentiviruses, both viruses use receptors that target the virus to a subset of cells that are pivotal to the acquired immune response. | lld:pubmed |
| pubmed-article:14976315 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14976315 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:14976315 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:14976315 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14976315 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:14976315 | pubmed:issn | 1095-9203 | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:IkedaYasuhiro... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:TakeuchiYasuh... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:MiyazawaTakay... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:WillettBrian... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:HosieMargaret... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:ShimojimaMasa... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:AkashiHiroomi... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:McMonagleEliz... | lld:pubmed |
| pubmed-article:14976315 | pubmed:author | pubmed-author:HainingHayley... | lld:pubmed |
| pubmed-article:14976315 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:14976315 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:14976315 | pubmed:volume | 303 | lld:pubmed |
| pubmed-article:14976315 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14976315 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14976315 | pubmed:pagination | 1192-5 | lld:pubmed |
| pubmed-article:14976315 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:14976315 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:14976315 | pubmed:articleTitle | Use of CD134 as a primary receptor by the feline immunodeficiency virus. | lld:pubmed |
| pubmed-article:14976315 | pubmed:affiliation | Department of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. | lld:pubmed |
| pubmed-article:14976315 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14976315 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:14976315 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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