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pubmed-article:1497359pubmed:abstractTextPyoderma gangrenosum is a chronic inflammatory ulcerative skin disease of unknown origin, often associated with various diseases including inflammatory bowel disease, inflammatory arthritis, monoclonal gammopathies, hepatitis, and myeloproliferative disorders. Treatment of associated systemic disorders may improve the ulcers, but lesions may be recalcitrant and persist for months to years. Therapy for pyoderma gangrenosum includes high-dose systemic corticosteroids, sulfa drugs such as sulfasalazine, clofazimine, and immunosuppressive agents such as mercaptopurine and azathioprine; these drugs are sometimes ineffective.lld:pubmed
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pubmed-article:1497359pubmed:articleTitleTreatment of pyoderma gangrenosum with cyclosporine.lld:pubmed
pubmed-article:1497359pubmed:affiliationDepartment of Dermatology, Hospital of the University of Pennsylvania, Philadelphia.lld:pubmed
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