Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP).

Source:http://linkedlifedata.com/resource/pubmed/id/14972523

Virology 2004 Jan 20 318 2 542-55

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14972523