| pubmed-article:1491606 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1491606 | lifeskim:mentions | umls-concept:C0021289 | lld:lifeskim |
| pubmed-article:1491606 | lifeskim:mentions | umls-concept:C0015689 | lld:lifeskim |
| pubmed-article:1491606 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:1491606 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:1491606 | pubmed:dateCreated | 1993-3-1 | lld:pubmed |
| pubmed-article:1491606 | pubmed:abstractText | Whether docosahexaenoic acid (22:6n-3) is an essential nutrient for term or preterm infants, or if not, the quantity of dietary linolenic acid (18:3n-3) needed to support sufficient synthesis of 22:6n-3 for assimilation in the central nervous system is unknown. Infants fed formulas have lower plasma and red blood cell (RBC) levels of 22:6n-3 than breast fed infants. No relationship between the intake of 18:3n-3 in formula (0.8 or 4.5% of fatty acids, 18:2n-6/18:3n-3 ratio 35:1 or 7:1, respectively) and the infant's RBC 22:6n-3 was found. Premature infants (< 33 wk gestation) also showed a decrease in RBC 22:6n-3 during feeding with formula containing 18:3n-3 as the only n-3 fatty acid. However, a marked decrease in plasma and RBC 22:6n-3 occurred between premature birth and the start of full enteral feeding at 1-2 wk of age. This was not reversed by breast milk or formula feeding. Piglets, which are appropriate for studies of infant lipid metabolism, had decreased brain synaptic plasma membrane, retina and liver 22:6n-3 and increased 22:5n-6 when fed formula with 0.8% fatty acids (0.3% of kcal) as 18:3n-3. Formula with 4.0% fatty acids (1.7% of kcal) as 18:3n-3 resulted in similar accretion of 22:6n-3 in the organs compared to milk fed animals. The studies suggest the dietary requirement for 18:3n-3 in term animals in energy balance exceeds 0.3% diet kcal.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:1491606 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1491606 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1491606 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1491606 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1491606 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1491606 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1491606 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1491606 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1491606 | pubmed:issn | 0024-4201 | lld:pubmed |
| pubmed-article:1491606 | pubmed:author | pubmed-author:InnisS MSM | lld:pubmed |
| pubmed-article:1491606 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1491606 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:1491606 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1491606 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1491606 | pubmed:pagination | 879-85 | lld:pubmed |
| pubmed-article:1491606 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:1491606 | pubmed:meshHeading | pubmed-meshheading:1491606-... | lld:pubmed |
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| pubmed-article:1491606 | pubmed:meshHeading | pubmed-meshheading:1491606-... | lld:pubmed |
| pubmed-article:1491606 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1491606 | pubmed:articleTitle | n-3 fatty acid requirements of the newborn. | lld:pubmed |
| pubmed-article:1491606 | pubmed:affiliation | Department of Paediatrics, University of British Columbia, Vancouver, Canada. | lld:pubmed |
| pubmed-article:1491606 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1491606 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1491606 | lld:pubmed |
