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pubmed-article:14871078pubmed:abstractTextA new, stereoselective method for the synthesis of substituted tetrahydrofurans from gamma-hydroxy alkenes that forms both a C-C and a C-O bond with diastereoselectivities of up to >20:1 is described. Initial mechanistic studies that suggest the reactions proceed via the intramolecular insertion of an olefin into a Pd(Ar)(OR) intermediate are discussed.lld:pubmed
pubmed-article:14871078pubmed:languageenglld:pubmed
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pubmed-article:14871078pubmed:authorpubmed-author:WolfeJohn PJPlld:pubmed
pubmed-article:14871078pubmed:authorpubmed-author:RossiMichael...lld:pubmed
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pubmed-article:14871078pubmed:pagination1620-1lld:pubmed
pubmed-article:14871078pubmed:dateRevised2008-1-17lld:pubmed
pubmed-article:14871078pubmed:year2004lld:pubmed
pubmed-article:14871078pubmed:articleTitleStereoselective synthesis of tetrahydrofurans via the palladium-catalyzed reaction of aryl bromides with gamma-hydroxy alkenes: evidence for an unusual intramolecular olefin insertion into a Pd(Ar)(OR) intermediate.lld:pubmed
pubmed-article:14871078pubmed:affiliationDepartment of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109-1055, USA. jpwolfe@umich.edulld:pubmed
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