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pubmed-article:14766712pubmed:abstractTextThe pharmacokinetics of remifentanil, an opioid analgesic metabolized by non-specific esterases, and its principal metabolite, remifentanil acid (RA), which is excreted via the kidneys, were assessed as part of an open-label safety study in intensive care unit (ICU) patients with varying degrees of renal impairment.lld:pubmed
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pubmed-article:14766712pubmed:articleTitlePharmacokinetics of remifentanil and its major metabolite, remifentanil acid, in ICU patients with renal impairment.lld:pubmed
pubmed-article:14766712pubmed:affiliationMedeval Ltd, Skelton House, Manchester Science Park, Lloyd Street North, Manchester M15 6SH, UK. m.pitsiu@medeval.comlld:pubmed
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