| pubmed-article:1476308 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0010453 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0019944 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0007301 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C1706515 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0025519 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C1704640 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:1476308 | lifeskim:mentions | umls-concept:C0331858 | lld:lifeskim |
| pubmed-article:1476308 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:1476308 | pubmed:dateCreated | 1993-2-2 | lld:pubmed |
| pubmed-article:1476308 | pubmed:abstractText | Explant cultures were set up, using articular cartilage obtained from metatarsophalangeal joints of 11 horses. Explants from 2 horses were used to determine culture conditions appropriate for tissue viability. The cartilage explants maintained steady-state metabolism of proteoglycans during a 13-day evaluation period. The metabolic response of equine articular cartilage to incubation with recombinant human interleukin 1 (0.01 to 100 ng/ml) was studied, using cartilage obtained from the remaining 9 horses, age of which ranged from 3 months to 20 years. Interleukin 1 induced a dose-dependent release of glycosaminoglycan from the matrix during a 3-day incubation period. It also caused dose-dependent inhibition of glycosaminoglycan synthesis during a 3-hour pulse-labeling period. Explants obtained from older horses were significantly (P < 0.05) less responsive to interleukin 1, with respect to synthesis and release of glycosaminoglycan. | lld:pubmed |
| pubmed-article:1476308 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1476308 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476308 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1476308 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476308 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476308 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1476308 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:1476308 | pubmed:issn | 0002-9645 | lld:pubmed |
| pubmed-article:1476308 | pubmed:author | pubmed-author:StoverS MSM | lld:pubmed |
| pubmed-article:1476308 | pubmed:author | pubmed-author:WillettR ARA | lld:pubmed |
| pubmed-article:1476308 | pubmed:author | pubmed-author:MacDonaldM... | lld:pubmed |
| pubmed-article:1476308 | pubmed:author | pubmed-author:BentonH PHP | lld:pubmed |
| pubmed-article:1476308 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1476308 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:1476308 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1476308 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1476308 | pubmed:pagination | 2278-85 | lld:pubmed |
| pubmed-article:1476308 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:meshHeading | pubmed-meshheading:1476308-... | lld:pubmed |
| pubmed-article:1476308 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1476308 | pubmed:articleTitle | Regulation of matrix metabolism in equine cartilage explant cultures by interleukin 1. | lld:pubmed |
| pubmed-article:1476308 | pubmed:affiliation | Department of Veterinary Anatomy, University of California, Davis 95616. | lld:pubmed |
| pubmed-article:1476308 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1476308 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1476308 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1476308 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1476308 | lld:pubmed |
