| pubmed-article:1472385 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C0205208 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C0002085 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C1317973 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C0183683 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C0344211 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C1521721 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C1514433 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C0332283 | lld:lifeskim |
| pubmed-article:1472385 | lifeskim:mentions | umls-concept:C1171411 | lld:lifeskim |
| pubmed-article:1472385 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1472385 | pubmed:dateCreated | 1993-2-2 | lld:pubmed |
| pubmed-article:1472385 | pubmed:abstractText | This article describes a method for determining whether a particular nucleic acid sequence is present in a sample and for discriminating between any two nucleic acid sequences if such sequences differ only by a single nucleotide. The method entails extension of a novel two-component primer on templates that may or may not include a target nucleic acid sequence. The 3' portion of the primer is complementary to a portion of the template adjacent to the target sequence (for example, the polymorphic nucleotide). The 5' portion of the primer is complementary to a different preselected nucleic acid sequence. Extension of the 3' portion of the primer with a labeled deoxynucleoside triphosphate yields a labeled extension product, but only if the template includes the target sequence. The presence of such a labeled primer-extension product is detected by hybridization of the 5' portion to the preselected sequence. The preselected sequence is immobilized on a solid support. The method has been applied to genotyping individuals for the two-allele polymorphism of the human tyrosinase gene. | lld:pubmed |
| pubmed-article:1472385 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1472385 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1472385 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1472385 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1472385 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1472385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1472385 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1472385 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1472385 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1472385 | pubmed:issn | 1050-3862 | lld:pubmed |
| pubmed-article:1472385 | pubmed:author | pubmed-author:WallaceR BRB | lld:pubmed |
| pubmed-article:1472385 | pubmed:author | pubmed-author:KaplanB EBE | lld:pubmed |
| pubmed-article:1472385 | pubmed:author | pubmed-author:EhsaniAA | lld:pubmed |
| pubmed-article:1472385 | pubmed:author | pubmed-author:UgozzoliLL | lld:pubmed |
| pubmed-article:1472385 | pubmed:author | pubmed-author:WahlqvistJ... | lld:pubmed |
| pubmed-article:1472385 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1472385 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:1472385 | pubmed:geneSymbol | TYR | lld:pubmed |
| pubmed-article:1472385 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1472385 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1472385 | pubmed:pagination | 107-12 | lld:pubmed |
| pubmed-article:1472385 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:meshHeading | pubmed-meshheading:1472385-... | lld:pubmed |
| pubmed-article:1472385 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1472385 | pubmed:articleTitle | Detection of specific alleles by using allele-specific primer extension followed by capture on solid support. | lld:pubmed |
| pubmed-article:1472385 | pubmed:affiliation | Department of Molecular Biochemistry, Beckman Research Institute of the City of Hope, Duarte, California. | lld:pubmed |
| pubmed-article:1472385 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1472385 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1472385 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1472385 | lld:pubmed |
