| pubmed-article:14699960 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14699960 | lifeskim:mentions | umls-concept:C0027752 | lld:lifeskim |
| pubmed-article:14699960 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:14699960 | lifeskim:mentions | umls-concept:C1704644 | lld:lifeskim |
| pubmed-article:14699960 | lifeskim:mentions | umls-concept:C0439234 | lld:lifeskim |
| pubmed-article:14699960 | pubmed:dateCreated | 2003-12-31 | lld:pubmed |
| pubmed-article:14699960 | pubmed:abstractText | Nerve growth factor (NGF) is required for the survival of developing sympathetic and sensory neurons. In the absence of NGF, these neurons undergo protein synthesis-dependent apoptosis. Ten years have gone by since the first reports of specific genes being upregulated during NGF deprivation-induced cell death. Over the last decade, a few additional genes (DP5, Bim, SM-20) have been added to a list that began with cyclin D1 and c-jun. In this chapter, we discuss the evidence that these genes act as regulators of neuronal cell death. We also suggest a hypothesis for how one gene, SM-20, may function to suppress a self-protection mechanism in NGF-deprived neurons. | lld:pubmed |
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| pubmed-article:14699960 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:14699960 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:14699960 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14699960 | pubmed:issn | 0079-6123 | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:CrowderRobert... | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:FreemanRobert... | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:StraubJennife... | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:XieLiangL | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:BurchRobert... | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:LombDavid JDJ | lld:pubmed |
| pubmed-article:14699960 | pubmed:author | pubmed-author:SchoellMatthe... | lld:pubmed |
| pubmed-article:14699960 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14699960 | pubmed:volume | 146 | lld:pubmed |
| pubmed-article:14699960 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14699960 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14699960 | pubmed:pagination | 111-26 | lld:pubmed |
| pubmed-article:14699960 | pubmed:dateRevised | 2011-9-2 | lld:pubmed |
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| pubmed-article:14699960 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:14699960 | pubmed:articleTitle | NGF deprivation-induced gene expression: after ten years, where do we stand? | lld:pubmed |
| pubmed-article:14699960 | pubmed:affiliation | Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA. Robert_Freeman@urmc.rochester.edu | lld:pubmed |
| pubmed-article:14699960 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14699960 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:14699960 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:14699960 | pubmed:publicationType | Historical Article | lld:pubmed |
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