Novel phenolic thiazoles compounds were prepared which demonstrated potent antioxidant activity and potent in vivo neuroprotection in mitochondrial toxin models and also possess good oral bioavailability.
Department of Medicinal Chemistry, Ipsen Research Laboratories, Institute Henri Beaufour, 5 Avenue du Canada, 91966 Les Ulis Cedex, France. jeremiah.harnett@ipsen.com
