| pubmed-article:14652019 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14652019 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:14652019 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:14652019 | lifeskim:mentions | umls-concept:C0074129 | lld:lifeskim |
| pubmed-article:14652019 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:14652019 | lifeskim:mentions | umls-concept:C0599894 | lld:lifeskim |
| pubmed-article:14652019 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
| pubmed-article:14652019 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:14652019 | pubmed:dateCreated | 2003-12-3 | lld:pubmed |
| pubmed-article:14652019 | pubmed:abstractText | Scavenger receptor class B type I (SR-BI) is an HDL receptor that mediates selective HDL lipid uptake. Peroxisomes play an important role in lipid metabolism and peroxisomal targeting signal type 1 (PTS1)-containing proteins are translocated to peroxisomes by the peroxisomal targeting import receptor, Pex5p. We have previously identified a PTS1 motif in the intracellular domain of rat SR-BI. Here, we examine the possible interaction between Pex5p and SR-BI. Expression of a Flag-tagged intracellular domain of SR-BI resulted in translocation to the peroxisome as demonstrated by double labeling with anti-Flag IgG and anti-catalase IgG analyzed by confocal microscopy. Immunoprecipitation experiments with anti-SR-BI antibody showed that Pex5p co-precipitated with SR-BI. However, when an antibody against Pex5p was used for immunoprecipitation, only the 57kDa, non-glycosylated form, of SR-BI co-precipitated. We conclude that the PTS1 domain of SR-BI is functional and can mediate peroxisomal interaction via Pex5p, in vitro. | lld:pubmed |
| pubmed-article:14652019 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14652019 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14652019 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14652019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14652019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:14652019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14652019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14652019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:14652019 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14652019 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14652019 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:14652019 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:AbergMaria... | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:ErikssonPeter... | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:CarlssonBjörn... | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:CarlssonLena... | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:JohnsonMagnus... | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:JohanssonJenn... | lld:pubmed |
| pubmed-article:14652019 | pubmed:author | pubmed-author:SvenssonPer... | lld:pubmed |
| pubmed-article:14652019 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14652019 | pubmed:day | 26 | lld:pubmed |
| pubmed-article:14652019 | pubmed:volume | 312 | lld:pubmed |
| pubmed-article:14652019 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14652019 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14652019 | pubmed:pagination | 1325-34 | lld:pubmed |
| pubmed-article:14652019 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:14652019 | pubmed:meshHeading | pubmed-meshheading:14652019... | lld:pubmed |
| pubmed-article:14652019 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14652019 | pubmed:articleTitle | Interaction of scavenger receptor class B type I with peroxisomal targeting receptor Pex5p. | lld:pubmed |
| pubmed-article:14652019 | pubmed:affiliation | Research Centre for Endocrinology and Metabolism (RCEM), Department of Internal Medicine, The Sahlgrenska Academy at Göteborg University, S-413 45, Göteborg, Sweden. Magnus.Johnson@medic.gu.se | lld:pubmed |
| pubmed-article:14652019 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14652019 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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