| pubmed-article:14645707 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0031886 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0205102 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0035553 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C1550548 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C1555714 | lld:lifeskim |
| pubmed-article:14645707 | lifeskim:mentions | umls-concept:C1705654 | lld:lifeskim |
| pubmed-article:14645707 | pubmed:issue | 25 | lld:pubmed |
| pubmed-article:14645707 | pubmed:dateCreated | 2003-12-10 | lld:pubmed |
| pubmed-article:14645707 | pubmed:abstractText | We have proposed a cancer treatment modality based on poliovirus chimeras replicating under the translational control of an internal ribosomal entry site (IRES) derived from human rhinovirus type 2. Insertion of the heterologous IRES causes a neuron-specific propagation deficit and eliminates neurovirulence inherent in poliovirus without affecting viral growth in cells derived from malignant gliomas. We now report the elucidation of a molecular mechanism responsible for the cell type-specific defect mediated by the rhinovirus IRES. Rhinovirus IRES function in neuronal cell types depends on specific structural elements within the 3' non-translated region of the viral genome. Our observations suggest long-range interactions between the IRES and the 3' terminus that control IRES-mediated gene expression and virus propagation. | lld:pubmed |
| pubmed-article:14645707 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14645707 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14645707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14645707 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14645707 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:14645707 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:14645707 | pubmed:author | pubmed-author:GromeierMatth... | lld:pubmed |
| pubmed-article:14645707 | pubmed:author | pubmed-author:FlorezPaolaP | lld:pubmed |
| pubmed-article:14645707 | pubmed:author | pubmed-author:DobrikovaElen... | lld:pubmed |
| pubmed-article:14645707 | pubmed:author | pubmed-author:BradrickShelt... | lld:pubmed |
| pubmed-article:14645707 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14645707 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:14645707 | pubmed:volume | 100 | lld:pubmed |
| pubmed-article:14645707 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14645707 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14645707 | pubmed:pagination | 15125-30 | lld:pubmed |
| pubmed-article:14645707 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:meshHeading | pubmed-meshheading:14645707... | lld:pubmed |
| pubmed-article:14645707 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14645707 | pubmed:articleTitle | Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region. | lld:pubmed |
| pubmed-article:14645707 | pubmed:affiliation | Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA. | lld:pubmed |
| pubmed-article:14645707 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14645707 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:14645707 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14645707 | lld:pubmed |
