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pubmed-article:14621757pubmed:dateCreated2003-11-18lld:pubmed
pubmed-article:14621757pubmed:abstractTextWe reviewed our clinical experience of allowing kidney regrafting with a repeated HLA mismatch. We also permitted a weakly positive B-cell cross-match. All patients who received a second or subsequent renal graft (n = 92) between January 1985 and June 1990 were analysed for graft survival. The overall 1-year graft survival was 70%. A repeated mismatch occurred in 29 of the patients at at least one HLA locus and their 1-year graft survival was 66%. The balance of the regrafts (63) were performed without a repeated mismatch, and their 1-year graft survival was 70%. Even a weakly positive B-cell cross-match was deleterious; when a grafting with a repeated mismatch was performed only one out of five grafts survived. Our results indicate that retransplantation of renal grafts with a repeated mismatch in the HLA A or B locus can be performed without a negative influence on transplant outcome provided that both the T- and B-cell cross-matches are negative.lld:pubmed
pubmed-article:14621757pubmed:languageenglld:pubmed
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pubmed-article:14621757pubmed:authorpubmed-author:LewénGGlld:pubmed
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pubmed-article:14621757pubmed:volume5 Suppl 1lld:pubmed
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pubmed-article:14621757pubmed:paginationS140-2lld:pubmed
pubmed-article:14621757pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:14621757pubmed:year1992lld:pubmed
pubmed-article:14621757pubmed:articleTitleIs repeated mismatching at regrafting deleterious?lld:pubmed
pubmed-article:14621757pubmed:affiliationDepartment of Surgery (Transplantation Unit), University Hospital, Uppsala, Sweden.lld:pubmed
pubmed-article:14621757pubmed:publicationTypeJournal Articlelld:pubmed