A first outbreak of serogroup C meningococcal disease occurred in the province of Quebec in 1990-1992 and lead to a mass immunization campaign using polysaccharide vaccines. In 2001, a second outbreak was identified and a mass vaccination campaign was carried out, using the newly licensed conjugate vaccine. Clinical, epidemiological, economic and social studies were instrumental in the decision making for implementing these control programs.
Département de médecine sociale et préventive, Université Laval, Pavillon de l'Est, 2180, chemin Sainte-Foy, local 1110, Québec, G1K 7P4 Canada. philippe.Dewals@msp.ulaval.ca