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pubmed-article:14597938pubmed:abstractTextThe presence of coronary collateral vessels has been associated with improved clinical outcome in patients with coronary artery disease. Animal experiments have shown that hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) can promote angiogenesis in ischemic tissues in a cholesterol-independent manner. We hypothesized that statin therapy is associated with increased coronary collateral formation in patients with severe coronary artery disease.lld:pubmed
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pubmed-article:14597938pubmed:articleTitleStatin use is associated with enhanced collateralization of severely diseased coronary arteries.lld:pubmed
pubmed-article:14597938pubmed:affiliationPreventive Cardiology Center, Division of Cardiology, and Department of Medicine, New England Medical Center Hospitals, Boston, Mass, USA.lld:pubmed
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