Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.

Source:http://linkedlifedata.com/resource/pubmed/id/14555504

Clin. Cancer Res. 2003 Oct 1 9 12 4340-6

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14555504