| pubmed-article:14550545 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0521447 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0332197 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C1881708 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0332472 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C1547179 | lld:lifeskim |
| pubmed-article:14550545 | lifeskim:mentions | umls-concept:C0667050 | lld:lifeskim |
| pubmed-article:14550545 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:14550545 | pubmed:dateCreated | 2003-10-10 | lld:pubmed |
| pubmed-article:14550545 | pubmed:abstractText | Crosslinking of the WEHI 231 lymphoma B cell receptor (BCR) leads to growth arrest followed by apoptosis. In a study of the role of lysosomal cysteine proteinases in BCR-mediated apoptosis we provide evidence that commitment to apoptosis correlates with a time-dependent increase in caspase and cathepsin activities. We also show that activation of cathepsins is a caspase-independent process, and caspase cascade activation is independent of lysosomal endopeptidases. BCR-induced nuclear fragmentation was not prevented, but rather delayed in the absence of detectable caspase and cathepsin activities, suggesting that BCR-driven apoptosis of these cells may use an alternative proteolytic mechanism independent of caspases and cathepsins. | lld:pubmed |
| pubmed-article:14550545 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14550545 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14550545 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14550545 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:14550545 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:14550545 | pubmed:author | pubmed-author:TurkBorisB | lld:pubmed |
| pubmed-article:14550545 | pubmed:author | pubmed-author:Mlinaric-Rasc... | lld:pubmed |
| pubmed-article:14550545 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14550545 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:14550545 | pubmed:volume | 553 | lld:pubmed |
| pubmed-article:14550545 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14550545 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14550545 | pubmed:pagination | 51-5 | lld:pubmed |
| pubmed-article:14550545 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:meshHeading | pubmed-meshheading:14550545... | lld:pubmed |
| pubmed-article:14550545 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14550545 | pubmed:articleTitle | B cell receptor-mediated nuclear fragmentation proceeds in WEHI 231 cells in the absence of detectable DEVDase and FRase activity. | lld:pubmed |
| pubmed-article:14550545 | pubmed:affiliation | Faculty of Pharmacy, University of Ljubljana, Slovenia. irena.mlinaric@ffa.uni-lj.si | lld:pubmed |
| pubmed-article:14550545 | pubmed:publicationType | Journal Article | lld:pubmed |
