SEN virus (SENV) was discovered in 1999 as a DNA virus with hepatotropic properties. Nine genotypes (A-I) have been identified with genotypes D and H being more prevalent in cases of chronic hepatitis. Attempts to determine whether SENV causes liver disease have been hampered by limited diagnostic testing.
Department of Medicine, Liver Diseases Unit, Health Sciences Centre, John Buhler Research Centre, University of Manitoba, 803-715 McDermot Avenue, Winnipeg, Man., Canada MB R3E 3P4.