| pubmed-article:14510381 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C0008109 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C0085732 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C1515877 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:14510381 | lifeskim:mentions | umls-concept:C0140694 | lld:lifeskim |
| pubmed-article:14510381 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:14510381 | pubmed:dateCreated | 2003-9-26 | lld:pubmed |
| pubmed-article:14510381 | pubmed:abstractText | The synthesis of a novel 2-5A-antisense chimera having two molecules of 2-5A tetramer at the 5'-terminus of the antisense moiety with an ethylene glycol linker is described. The ability of the synthesized 2-5A antisense chimeras to activate RNase L was estimated by monitoring the cleavage of a target RNA by the activated RNase L. It was found that the double-headed 2-5A-antisense chimera linked with two molecules of a butanediol linker more efficiently cleaved the target RNA as compared with the single-headed 2-5A-antisense chimera and the double-headed 2-5A-antisense chimera linked with a molecule of the butanediol linker. | lld:pubmed |
| pubmed-article:14510381 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14510381 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14510381 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14510381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14510381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14510381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14510381 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14510381 | pubmed:author | pubmed-author:UenoYoshihito... | lld:pubmed |
| pubmed-article:14510381 | pubmed:author | pubmed-author:KitadeYukioY | lld:pubmed |
| pubmed-article:14510381 | pubmed:author | pubmed-author:OkataniShusak... | lld:pubmed |
| pubmed-article:14510381 | pubmed:author | pubmed-author:YamadaYuukiY | lld:pubmed |
| pubmed-article:14510381 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14510381 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14510381 | pubmed:pagination | 63-4 | lld:pubmed |
| pubmed-article:14510381 | pubmed:dateRevised | 2011-6-17 | lld:pubmed |
| pubmed-article:14510381 | pubmed:meshHeading | pubmed-meshheading:14510381... | lld:pubmed |
| pubmed-article:14510381 | pubmed:meshHeading | pubmed-meshheading:14510381... | lld:pubmed |
| pubmed-article:14510381 | pubmed:meshHeading | pubmed-meshheading:14510381... | lld:pubmed |
| pubmed-article:14510381 | pubmed:meshHeading | pubmed-meshheading:14510381... | lld:pubmed |
| pubmed-article:14510381 | pubmed:meshHeading | pubmed-meshheading:14510381... | lld:pubmed |
| pubmed-article:14510381 | pubmed:meshHeading | pubmed-meshheading:14510381... | lld:pubmed |
| pubmed-article:14510381 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14510381 | pubmed:articleTitle | Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L. | lld:pubmed |
| pubmed-article:14510381 | pubmed:affiliation | Department of Biomolecular Science, Faculty of Engineering, Gifu University, Yanagido, Gifu 501-1193, Japan. | lld:pubmed |
| pubmed-article:14510381 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14510381 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
