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pubmed-article:14506182pubmed:abstractTextThe selection and characterization of anti-MUC-1 single-chain antibody fragments (scFv) is a first step toward the construction of new anticancer molecules designed for optimal blood clearance and tumor penetration. The mucin MUC-1 was chosen as an antigen because it is abundantly expressed on epithelial cancers in an aberrantly glycosylated form, making it structurally and antigenically distinct from MUC-1 expressed on normal cells.lld:pubmed
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pubmed-article:14506182pubmed:articleTitleSelection and characterization of anti-MUC-1 scFvs intended for targeted therapy.lld:pubmed
pubmed-article:14506182pubmed:affiliationUniversity of California Davis Medical Center, Sacramento, California 95816, USA.lld:pubmed
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