Linked Life Data

14504054

Source:http://linkedlifedata.com/resource/pubmed/id/14504054

Statements in which the resource exists.
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pubmed-article:14504054pubmed:abstractTextMicrosatellite instability (MSI) is due to defective DNA mismatch repair (MMR) and has been detected at various rates in colorectal carcinoma (CRC). The role of MSI in colorectal tumorigenesis was assessed further in this study by both microsatellite analysis of two CRC subsets [unselected patients (n = 215) and patients <50 years of age (n = 95)], and mutation screening of the two major MMR genes MLH1 and MSH2 among familial CRC cases.lld:pubmed
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pubmed-article:14504054pubmed:articleTitleMicrosatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases.lld:pubmed
pubmed-article:14504054pubmed:affiliationIstituto Chimica Biomolecolare-Sezione di Sassari, C.N.R., Tramariglio, Alghero, Santa Maria La Palma, Italy.lld:pubmed
pubmed-article:14504054pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:14504054pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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