| pubmed-article:14316946 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0009498 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0204727 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C1414290 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0205439 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
| pubmed-article:14316946 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
| pubmed-article:14316946 | pubmed:dateCreated | 1965-10-1 | lld:pubmed |
| pubmed-article:14316946 | pubmed:abstractText | At least 3 complement factors were found necessary for the conversion of the thermolabile intermediate complex EAC'1a,4,2a to a thermostable state. One of these factors is the earlier described beta(1C)-globulin. The second, a heretofore unrecorded serum protein, beta(1F)-globulin. The third factor has not yet been defined as a discrete serum protein entity. Kinetic experiments indicated that beta(1C) reacted prior to beta(1F), which in turn seemed to precede the third factor in the reaction sequence. Therefore, the 3 components were tentatively designated the third (C'3), the fifth (C'5), and the sixth (C'6) components of complement, respectively. A procedure was developed allowing the isolation of highly purified beta(1C)-(C'3) and beta(1F)-globulin (C'5) and of partially purified C'6. With respect to its function in immune hemolysis, beta(1F)-globulin or C'5 was found to be closely dependent on the simultaneous presence of C'6. The hypothesis that C'5 and C'6 form a functional unit was supported by the finding that both components interact with each other in solution resulting in the formation of a complex. A similar complex was also found in fresh human serum. | lld:pubmed |
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| pubmed-article:14316946 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:14316946 | pubmed:citationSubset | OM | lld:pubmed |
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| pubmed-article:14316946 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14316946 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:14316946 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:14316946 | pubmed:author | pubmed-author:MUELLER-EBERH... | lld:pubmed |
| pubmed-article:14316946 | pubmed:author | pubmed-author:NILSSONU RUR | lld:pubmed |
| pubmed-article:14316946 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14316946 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:14316946 | pubmed:volume | 122 | lld:pubmed |
| pubmed-article:14316946 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14316946 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14316946 | pubmed:pagination | 277-98 | lld:pubmed |
| pubmed-article:14316946 | pubmed:dateRevised | 2010-9-21 | lld:pubmed |
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| pubmed-article:14316946 | pubmed:meshHeading | pubmed-meshheading:14316946... | lld:pubmed |
| pubmed-article:14316946 | pubmed:year | 1965 | lld:pubmed |
| pubmed-article:14316946 | pubmed:articleTitle | ISOLATION OF BETA IF-GLOBULIN FROM HUMAN SERUM AND ITS CHARACTERIZATION AS THE FIFTH COMPONENT OF COMPLEMENT. | lld:pubmed |
| pubmed-article:14316946 | pubmed:publicationType | Journal Article | lld:pubmed |
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