| pubmed-article:1386989 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0162429 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0085584 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0599708 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0598411 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0598413 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C0813872 | lld:lifeskim |
| pubmed-article:1386989 | lifeskim:mentions | umls-concept:C1292733 | lld:lifeskim |
| pubmed-article:1386989 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1386989 | pubmed:dateCreated | 1992-9-23 | lld:pubmed |
| pubmed-article:1386989 | pubmed:abstractText | Rats were trained on a spatial delayed-nonmatching-to-sample (DNMTS) task and assigned by block randomization to one of four treatments: pyrithiamine-induced thiamine deficiency (PTD), PTD with administration of MK-801 after 12 days, control with MK-801 treatment, and control without MK-801. After 15 days of treatment followed by 21 days of recovery, the PTD rats showed significant deficits for DNMTS accuracy at retention intervals (RI) that ranged from 3.0 s to 15.0 s, the RIs that produced 75% accuracy on DNMTS in staircase training, and the rate at which a novel radial arm maze task was learned. The PTD-treated rats had consistent lesions in the thalamus and the mammillary bodies. MK-801 protected rats from both behavioral deficits and brain lesions (assessed quantitatively and qualitatively) that were produced by the PTD treatment. | lld:pubmed |
| pubmed-article:1386989 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1386989 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1386989 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1386989 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1386989 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1386989 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1386989 | pubmed:issn | 0735-7044 | lld:pubmed |
| pubmed-article:1386989 | pubmed:author | pubmed-author:MainR KRK | lld:pubmed |
| pubmed-article:1386989 | pubmed:author | pubmed-author:RobinsonJ KJK | lld:pubmed |
| pubmed-article:1386989 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1386989 | pubmed:volume | 106 | lld:pubmed |
| pubmed-article:1386989 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1386989 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1386989 | pubmed:pagination | 623-33 | lld:pubmed |
| pubmed-article:1386989 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:1386989 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1386989 | pubmed:articleTitle | MK-801 prevents brain lesions and delayed-nonmatching-to-sample deficits produced by pyrithiamine-induced encephalopathy in rats. | lld:pubmed |
| pubmed-article:1386989 | pubmed:affiliation | University of New Hampshire, Durham 03824. | lld:pubmed |
| pubmed-article:1386989 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1386989 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1386989 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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