| pubmed-article:13862360 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C0006280 | lld:lifeskim |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C1522318 | lld:lifeskim |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C0038477 | lld:lifeskim |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C0180431 | lld:lifeskim |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C0205549 | lld:lifeskim |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:13862360 | lifeskim:mentions | umls-concept:C0245296 | lld:lifeskim |
| pubmed-article:13862360 | pubmed:dateCreated | 1962-12-1 | lld:pubmed |
| pubmed-article:13862360 | pubmed:abstractText | The bronchodilator activity of 47 compounds on the isolated guinea-pig tracheal ring preparation and the coronary dilator activity on the dog heart-lung preparation is described. 1,3-Disubstituted xanthines and 6-thioxanthines (theophyllines and 6-thiotheophyllines) were more active as bronchodilators and as coronary dilators than were 3,7-disubstituted 6-thioxanthines (6-thiotheobromines) or 1,3,7-trisubstituted 6-thioxanthines (6-thiocaffeines). None of the 6-thioxanthines was of any interest as a diuretic and none of the 6-thiocaffeines was of any interest as a central stimulant. Structure-activity requirements for potent bronchodilator and coronary dilator activity are discussed. | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:language | eng | lld:pubmed |
| pubmed-article:13862360 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:citationSubset | OM | lld:pubmed |
| pubmed-article:13862360 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:13862360 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:13862360 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:13862360 | pubmed:issn | 0366-0826 | lld:pubmed |
| pubmed-article:13862360 | pubmed:author | pubmed-author:ARMITAGEA KAK | lld:pubmed |
| pubmed-article:13862360 | pubmed:author | pubmed-author:BOSWOODJJ | lld:pubmed |
| pubmed-article:13862360 | pubmed:author | pubmed-author:LARGEB JBJ | lld:pubmed |
| pubmed-article:13862360 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:13862360 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:13862360 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:13862360 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:13862360 | pubmed:pagination | 196-207 | lld:pubmed |
| pubmed-article:13862360 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:13862360 | pubmed:meshHeading | pubmed-meshheading:13862360... | lld:pubmed |
| pubmed-article:13862360 | pubmed:meshHeading | pubmed-meshheading:13862360... | lld:pubmed |
| pubmed-article:13862360 | pubmed:meshHeading | pubmed-meshheading:13862360... | lld:pubmed |
| pubmed-article:13862360 | pubmed:year | 1961 | lld:pubmed |
| pubmed-article:13862360 | pubmed:articleTitle | Structure-activity relationships in a series of 6-thioxanthines with bronchodilator and coronary dilator properties. | lld:pubmed |
| pubmed-article:13862360 | pubmed:publicationType | Journal Article | lld:pubmed |
