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pubmed-article:1384681pubmed:abstractTextPrevious cytogenetic analyses revealed t(6;20)(p21;q13) in two endometrial polyps. We karyotyped a large endometrial polyp in which 19 of 25 metaphase cells contained a t(1;6;4)(q21;p21;q13). Subsequent combined immunohistochemical/cytogenetic analysis showed all aberrant metaphase cells to be of mesenchymal derivation, whereas epithelial cells from the polyp were diploid. These studies indicate that rearrangement of chromosome band 6p21 is a characteristic cytogenetic aberration in the stromal component of endometrial polyps.lld:pubmed
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pubmed-article:1384681pubmed:articleTitleClonal 6p21 rearrangement is restricted to the mesenchymal component of an endometrial polyp.lld:pubmed
pubmed-article:1384681pubmed:affiliationDepartment of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115.lld:pubmed
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pubmed-article:1384681pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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