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pubmed-article:1381232pubmed:abstractTextBy analysis of the mouse 5-HT1C receptor gene we found that its coding region contains three introns. We next isolated cDNA and genomic clones for the closely related 5-HT2 receptor using a probe derived from the 5-HT1C receptor sequence. This probe also hybridized to an additional gene, called SRL (Serotonin Receptor Like). We have evidence demonstrating that it encodes the stomach fundus 5-HT receptor. Two introns are present within the coding regions of the mouse 5-HT2 receptor gene and the SRL gene at positions which correspond to those of introns in the 5-HT1C receptor gene. This intron distribution is unique and distinguishes these receptors from other members of the family of receptors coupled to G-proteins.lld:pubmed
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pubmed-article:1381232pubmed:articleTitleStructure of the mouse 5-HT1C, 5-HT2 and stomach fundus serotonin receptor genes.lld:pubmed
pubmed-article:1381232pubmed:affiliationPreclinical Research, Sandoz Pharma Ltd., Basel, Switzerland.lld:pubmed
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